Adding insult to injury, a measure of Chinese manufacturing slipped to a six month low for January and gave speculators a fresh excuse to target risk assets such as the Australian dollar.
While analysts emphasised that January data is heavily distorted by the timing of the Chinese Lunar holidays, the drop in the HSBC PMI was bound to cause ripples in already skittish markets.
Japan's Nikkei was already down 3.1 percent at its lowest since mid-November. Shanghai slipped 0.5 percent while MSCI's broadest index of Asia-Pacific shares outside Japan lost 1 percent.
Markets have now shed all the gains made on Wednesday when the region had hoped that aggressive rate hikes by Turkey would shore up its currency and ease the risk of capital flight.
Investors in Europe and the United States were less impressed, however, perhaps worried about the damage higher rates might do to economic growth in these countries.
The Dow ended Wednesday with losses of 1.19 percent, while the S&P 500 shed 1.02 percent. In Europe, the pan-regional FTSEurofirst 300 index fell 0.63 percent.
Indeed, when South Africa's central bank surprised by lifting its rates half a percentage point investors reacted by dumping the rand. Likewise, Turkey's lira saw most of its initial gains stripped away.
That in turn revived demand for safe havens such as the yen, Swiss franc and sovereign bonds. The U.S. dollar was stuck at 102.21, having shed a full yen overnight.
The euro also lost ground on the yen and Swiss franc, but was sidelined on the dollar at $1.3650.
Bonds benefited from the general mood of risk aversion with U.S. 10-year Treasury yields at 2.68 percent, having hit the lowest since mid-November on Wednesday.
FED STICKS TO TAPERING
The focus on safety was only sharpened by the Fed's well-flagged decision to trim its monthly bond buying program by a further $10 billion a month.
There had been some talk the wild swings in emerging markets might give the Fed pause for thought. Instead, Barclays economist Michael Gapen noted the Fed made no mention at all of financial markets in its statement.
"In our view, the type of volatility seen in recent weeks is insufficient to cause the committee to alter its policy stance, particularly so soon after tapering began," he added.
"We expect the committee to continue reducing the pace of asset purchases by $10bn at each upcoming FOMC meeting through September and then take a final $15bn reduction in October to conclude QE3."
Many seem to agree, with a Reuters poll of 17 primary dealers in the Treasury market finding all expected QE to be wound down this year.
The prospect of a steady withdrawal of stimulus coupled with improving economies in the developed world has attracted funds away from many emerging markets, particularly those with current account deficits and/or political troubles.
With Brazil, Turkey, South Africa and India all holding elections this year, policymakers are likely to be wary of hiking rates too much to avoid damaging economic growth.
The vulnerabilities in the emerging world were noted by the Reserve Bank of New Zealand when it decided to hold off on raising interest rates on Thursday.
The central bank kept rates at a record low of 2.5 percent but said it was likely to start tightening soon, given the strength of the domestic economy and growing inflationary pressures.
In commodity markets, gold found itself back in favour as a store of wealth at $1,263.56, having climbed over $10 on Wednesday.
Oil prices were modestly higher with U.S. crude 24 cents firmer at $97.60 a barrel, while Brent gained another 12 cents to $107.97 a barrel.